WHITEPAPER: Solving batch-mode specific challenges while producing best quality Grignard reagents

WHITEPAPER: Solving batch-mode specific challenges while producing best quality Grignard reagents

Grignard reagents, originally reported in the early 20th century, have become and still remain a useful tool for creating carbon-carbon bonds in the chemical industry. They found application in pharma, agrochemicals, perfumes, electronics, material science, energy storage, … Simultaneously, organomagnesium reagents remain a very active area in research. Yet, their synthesis mode hasn’t evolved much and most of large-scale Grignard production campaigns are carried out in batch mode. As a result, the chemical industry faces significant safety and quality issues when it comes to producing Grignard reagents.  Chemium has designed the MgFlow ® Technology in order to by-pass these obstacles,…
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CHEMIUM LAUNCHES MgFlow ® TECHNOLOGY AND REINVENTS GRIGNARD MANUFACTURING

CHEMIUM LAUNCHES MgFlow ® TECHNOLOGY AND REINVENTS GRIGNARD MANUFACTURING

Louvain-La-Neuve, September 29th 2022,Based on the Flow Chemistry concepts and advanced simulation techniques, CHEMIUM has developed a novel, safe, reliable and highly flexible continuous flow technology, to produce Grignard reagents at industrial scale.Discovered by Victor Grignard in 1900, this family of magnesium-based reagents is largely used in the industry for the key chemical transformation that leads to carbon-carbon bond formation, giving to chemists the ability to build or extend the carbon backbone of chemical structures. This amazing chemistry has proven to be a key element in the production of useful products in highly dynamic markets such as pharmaceutical, agrochemical or…
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