WHITEPAPER: Safe Industrial-Scale Production of Grignard Reagents in Continuous Mode, A Successful Paradigm Shift

WHITEPAPER: Safe Industrial-Scale Production of Grignard Reagents in Continuous Mode, A Successful Paradigm Shift

CHEMIUM is reshaping Grignard reagent manufacturing for the fine chemical, pharmaceutical, agrochemical and specialty chemicals industries. Based in Louvain-la-Neuve, Belgium, this innovative company with its proprietary continuous flow MgFlow ® technology, is taking this chemistry a huge step towards safer, more sustainable, and economically advantageous Grignard production at industrial scale. Supported by a strategic collaboration with Swiss CDMO partner Valsynthese, CHEMIUM’s approach marks a paradigm shift in overcoming the traditional limitations of batch processing, setting new standards in process reliability. Download the whitepaper
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WHITEPAPER: Solving batch-mode specific challenges while producing best quality Grignard reagents

WHITEPAPER: Solving batch-mode specific challenges while producing best quality Grignard reagents

Grignard reagents, originally reported in the early 20th century, have become and still remain a useful tool for creating carbon-carbon bonds in the chemical industry. They found application in pharma, agrochemicals, perfumes, electronics, material science, energy storage, … Simultaneously, organomagnesium reagents remain a very active area in research. Yet, their synthesis mode hasn’t evolved much and most of large-scale Grignard production campaigns are carried out in batch mode. As a result, the chemical industry faces significant safety and quality issues when it comes to producing Grignard reagents. Chemium has designed the MgFlow ® Technology in order to by-pass these obstacles, making…
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